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IU-1

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604013

IU-1 (USP14 inhibitor IU1) is a specific, small molecule inhibitor of deubiquitinating enzyme USP14 with IC50 of 4-5 uM. More details

$240 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IU-1, Biochemical
Full Product Name
IU-1
Product Synonym Names
USP14 inhibitor IU1
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
300.377
Suitability
DMSO: 30mg/mL (100mM)
Ethanol: 15mg/mL (50mM) (<1mg/mL refers to the product slightly soluble or insoluble)
Target
DUB
Receptor
USP14
Chemical Name
1-[1-(4-fluorophenyl)-2, 5-dimethylpyrrol-3-yl]-2-pyrrolidin-1-ylethanone
SMILES
CC1=CC(C(CN2CCCC2)=O)=C(C)N1C3=CC=C(F)C=C3
Molecular Formula
C18H21FN2O
CAS Number
314245-33-5

Product Categories/Family for IU-1 biochemical

Proteasome/Ubiquitin; Cancer

Structure of IU-1 biochemical

Iu-1 Biochemical – Cat# MBS3604013

Product References and Citations for IU-1 biochemical

1. Lee BH, et al. Nature. 2010 Sep 9; 467 (7312):179-84.
2. Nag DK, et al. Virus Res. 2012 Apr; 165 (1):103-6.
3. Lahaie N, et al. J Biol Chem. 2016 Mar 25; 291 (13):7156-70.
4. Min JW, et al. J Neurochem. 2017 Mar; 140 (5):826-833.

Other Notes

Small volumes of IU-1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IU-1 purchase

MBS3604013 is a biochemical targeting IU-1.
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