Ispinesib (SB-715992)

Name: Ispinesib (SB-715992); MyBioSource
Brand: MyBioSource
SKU: MBS3604139
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604139

A potent, selective, cell-permeable, allosteric inhibitor of Eg5 (mitotic kinesin KSP) with Ki of 2.3 nM. More details

$220 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ispinesib, Biochemical

Full Product Name

Ispinesib

Product Synonym Names

SB-715992; SB 715992; SB715992

Purity/Purification

98%

Preparation and Storage

Store at -20°C for 1 year.

Molecular Weight

517.06

Suitability

10mM in DMSO

Target

Kinesin

Receptor

KSP (HsEg5)

Pathway

Cytoskeleton/Cell Adhesion Molecules

Chemical Name

Benzamide, N-(3-aminopropyl)-N-[(1R)-1-[7-chloro-3, 4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]-2-methylpropyl]-4-methyl

SMILES

O=C(N(CCCN)[C@@H](C(N1CC2=CC=CC=C2)=NC3=C(C=CC(Cl)=C3)C1=O)C(C)C)C4=CC=C(C)C=C4

Molecular Formula

C30H33ClN4O2

CAS Number

336113-53-2

Product Categories/Family for Ispinesib biochemical

Breast Cancer; Cytoskeleton/Cell Adhesion Molecules; Cancer

Product References and Citations for Ispinesib biochemical

1. Good JA, et al. J Med Chem. 2013 Mar 14; 56 (5):1878-93.
2. Purcell JW, et al. Clin Cancer Res. 2010 Jan 15; 16 (2):566-76.
3. Luo L, et al. Nat Chem Biol. 2007 Nov; 3 (11):722-6. Epub 2007 Oct 7.

Other Notes

Small volumes of Ispinesib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ispinesib purchase

MBS3604139 is a biochemical targeting Ispinesib.