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SB 525334

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604223

SB 525334 is a potent and selective inhibitor of TGF-beta1 receptor (ALK5) inhibitor with IC50 of 14,5 nM. More details

$215 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SB 525334, Biochemical
Full Product Name
SB 525334
Product Synonym Names
SB-525334; SB525334
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
343.4249
Suitability
DMSO: >=46mg/mL
Target
TGFBR
Receptor
TGFbetaR1 (ALK5); ALK5; ALK4
Chemical Name
Quinoxaline, 6-[2-(1, 1-dimethylethyl)-5-(6-methyl-2-pyridinyl)-1H-imidazol-4-yl]
SMILES
CC1=CC=CC(C2=C(C3=CC=C4N=CC=NC4=C3)N=C(C(C)(C)C)N2)=N1
Molecular Formula
C21H21N5
CAS Number
356559-20-1

Product Categories/Family for SB 525334 biochemical

TGF-beta/Smad; Cancer

Structure of SB 525334 biochemical

Sb 525334 Biochemical – Cat# MBS3604223

Product References and Citations for SB 525334 biochemical

1. Grygielko ET, et al. J Pharmacol Exp Ther. 2005 Jun; 313 (3):943-51.
2. Laping NJ, et al. Clin Cancer Res. 2007 May 15; 13 (10):3087-99.
3. Thomas M, et al. Am J Pathol. 2009 Feb; 174 (2):380-9.
4. Kim YJ, et al. Anticancer Res. 2012 Mar; 32 (3):799-806.

Other Notes

Small volumes of SB 525334 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SB 525334 purchase

MBS3604223 is a biochemical targeting SB 525334.
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