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YM-201636

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604283

YM-201636 is a potent, selective PIKfyve inhibitor with IC50 of 33 nM, does not inhibits type Iigamma/Ialpha PtdInsP kinases even at 10 uM (p110alpha IC50=3.3 uM). More details

$240 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
YM-201636, Biochemical
Full Product Name
YM-201636
Product Synonym Names
YM 201636; YM201636
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
467.4793
Suitability
DMSO: >=47mg/mL
Target
PIKfyve
Receptor
p110alpha; PIKfyve
Chemical Name
3-Pyridinecarboxamide, 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3', 2':4, 5]furo[3, 2-d]pyrimidin-2-yl]phenyl]
SMILES
O=C(C1=CC=C(N)N=C1)NC2=CC=CC(C3=NC(N4CCOCC4)=C(OC5=NC=CC=C56)C6=N3)=C2
Molecular Formula
C25H21N7O3
CAS Number
371942-69-7

Product Categories/Family for YM-201636 biochemical

PI3K/Akt/mTOR signaling; Cancer

Structure of YM-201636 biochemical

Ym-201636 Biochemical – Cat# MBS3604283

Product References and Citations for YM-201636 biochemical

1. Jefferies HB, et al. EMBO Rep. 2008 Feb; 9 (2):164-70.
2. Osborne SL, et al. J Biol Chem. 2008 Feb 1; 283 (5):2804-13.
3. Ikonomov OC, et al. Biochem Biophys Res Commun. 2009 May 8; 382 (3):566-70.
4. Kerr MC, et al. EMBO J. 2010 Apr 21; 29 (8):1331-47.

Other Notes

Small volumes of YM-201636 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for YM-201636 purchase

MBS3604283 is a biochemical targeting YM-201636.
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