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SU-9516

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604300

A selective CDK2 inhibitor with IC50 of 22 nM; shows less potent for CDK1/CDK4(IC50=40/200 nM), no inhibition on PKC, EGFR, p38MAPK; decreases the phosphorylation of pRb, and increases caspase-3 activation. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SU-9516, Biochemical
Full Product Name
SU-9516
Product Synonym Names
SU9516; SU 9516
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
241.2453
Suitability
10mM in DMSO
Target
CDK
Receptor
CDK1; CDK2; CDK4; p38; PKC
Chemical Name
2H-Indol-2-one, 1, 3-dihydro-3-(1H-imidazol-5-ylmethylene)-5-methoxy-, (3Z)
SMILES
O=C1NC2=C(C=C(OC)C=C2)/C1=C/C3=CN=CN3
Molecular Formula
C13H11N3O2
CAS Number
377090-84-1

Product Categories/Family for SU-9516 biochemical

Angiogenesis; Cancer

Structure of SU-9516 biochemical

Su-9516 Biochemical – Cat# MBS3604300

Product References and Citations for SU-9516 biochemical

1. Lane ME, et al. Cancer Res. 2001 Aug 15; 61 (16):6170-7.
2. Gao N, et al. Mol Pharmacol. 2006 Aug; 70 (2):645-55.
3. Sarathy A, et al. Mol Ther. 2017 Apr 5. pii: S1525-0016 (17)30121-1.

Other Notes

Small volumes of SU-9516 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SU-9516 purchase

MBS3604300 is a biochemical targeting SU-9516.
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