Saracatinib (AZD0530)

Name: Saracatinib (AZD0530); MyBioSource
Brand: MyBioSource
SKU: MBS3604307
Price: 240 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604307

A potent, highly selective, orally available, dual Src/Abl kinase inhibitor with IC50 of 2.7, 4, 4 and 30 nM for c-Src, Yes, Lck and Abl, respectively. More details

$240 / 10 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Saracatinib, Biochemical

Full Product Name

Saracatinib

Product Synonym Names

AZD0530; AZD-0530; AZD 0530

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

542.0265

Suitability

DMSO: >=32mg/mL

Target

Src

Receptor

BLK; c-Kit; c-Src; c-Yes; EGFR; EGFR (L858R); EGFR (L861Q); EphA2; FGR; Fyn; Lck; Lyn; v-Abl; EGFRL861Q; EGFRL858R

Chemical Name

4-Quinazolinamine, N-(5-chloro-1, 3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]

SMILES

CN1CCN(CCOC2=CC3=NC=NC(NC4=C5OCOC5=CC=C4Cl)=C3C(OC6CCOCC6)=C2)CC1

Molecular Formula

C27H32ClN5O5

CAS Number

379231-04-6

Product Categories/Family for Saracatinib biochemical

Breast Cancer; Angiogenesis; Cancer

Product References and Citations for Saracatinib biochemical

1. Hennequin LF, et al. J Med Chem. 2006 Nov 2; 49 (22):6465-88.
2. Herynk MH, et al. Mol Cancer Ther. 2006 Dec; 5 (12):3023-31.
3. Chang YM, et al. Oncogene. 2008 Oct 23; 27 (49):6365-75.
4. Gwanmesia PM, et al. BMC Cancer. 2009 Feb 13; 9:53.

Other Notes

Small volumes of Saracatinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Saracatinib purchase

MBS3604307 is a biochemical targeting Saracatinib.