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PF-03049423

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604379

PF-03049423 is a potent, selective, orally active, and brain penetrant inhibitor of PDE5 with IC50 of 0.2 nM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PF-03049423, Biochemical
Full Product Name
PF-03049423
Product Synonym Names
PF 03049423
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
468.55
Target
PDE
Receptor
PDE
Chemical Name
3-[4-(2-Hydroxyethyl)-1-piperazinyl]-7-(6-methoxy-3-pyridinyl)-1-(2-propoxyethyl)-pyrido[3, 4-b]pyrazin-2(1H)-one
SMILES
CCCOCCN1C2=CC(=NC=C2N=C(C1=O)N3CCN(CC3)CCO)C4=CN=C(C=C4)OC.Cl
Molecular Formula
C24H32N6O4
CAS Number
402955-58-2

Product Categories/Family for PF-03049423 biochemical

Stroke; Angiogenesis; Neurological Disease

Structure of PF-03049423 biochemical

Pf-03049423 Biochemical – Cat# MBS3604379

Product References and Citations for PF-03049423 biochemical

1. Hughes RO, et al. J Med Chem. 2010 Mar 25; 53 (6):2656-60.
2. Di Cesare F, et al. J Stroke Cerebrovasc Dis. 2016 Mar; 25 (3):642-9.

Other Notes

Small volumes of PF-03049423 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-03049423 purchase

MBS3604379 is a biochemical targeting PF-03049423.
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