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CHIR-124

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604392

MBS3604392 is a biochemical targeting CHIR-124. CHIR-124 is a potent, selective Chk1 inhibitor with in vitro IC50 of 0.3 nM. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CHIR-124, Biochemical
Full Product Name
CHIR-124
Product Synonym Names
CHIR124; CHIR 124
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
419.91
Suitability
DMSO: 14mg/mL
Target
Chk
Receptor
Chk1; FLT3; Fyn; GSK-3; PDGFR
Chemical Name
2(1H)-Quinolinone, 4-[(3S)-1-azabicyclo[2.2.2]oct-3-ylamino]-3-(1H-benzimidazol-2-yl)-6-chloro
SMILES
O=C1NC2=C(C=C(Cl)C=C2)C(N[C@@H]3C[N@]4CC[C@]3([H])CC4)=C1C5=NC6=CC=CC=C6N5
Molecular Formula
C23H22ClN5O
CAS Number
405168-58-3

Product Categories/Family for CHIR-124 biochemical

Angiogenesis; Cancer

Structure of CHIR-124 biochemical

CHIR-124 Biochemical – Cat# MBS3604392

Product References and Citations for CHIR-124 biochemical

1. Tse AN, et al. Clin Cancer Res. 2007 Jan 15; 13 (2 Pt 1):591-602. 2. Tao Y, et al. Cell Cycle. 2009 Apr 15; 8 (8):1196-205. 3. Lee JH, et al. Proc Natl Acad Sci U S A. 2011 Dec 6; 108 (49):19629-34. 4. Seiler JA, et al. Mol Cell Biol. 2007 Aug; 27 (16):5806-18.

Other Notes

Small volumes of CHIR-124 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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