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Dovitinib (CHIR-258)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604393

MBS3604393 is a biochemical targeting Dovitinib. A novel, multitargeted RTK inhibitor of class III, IV, and V RTKs. More details

$220 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Dovitinib, Biochemical
Full Product Name
Dovitinib
Product Synonym Names
CHIR-258; TKI258; TKI-258; TKI 258; CHIR258; CHIR 258
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
392.4294
Suitability
DMSO: 25mg/mL
Target
FGFR
Receptor
c-Kit; FGFR1; FGFR3; FLT3; VEGFR3/FLT4
Chemical Name
2(1H)-Quinolinone, 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]
SMILES
CN1CCN(CC1)C2=CC3=C(C=C2)N/C(=C/4C(=C5C(=NC4=O)C=CC=C5F)N)/N3
Molecular Formula
C21H21FN6O
CAS Number
405169-16-6

Product Categories/Family for Dovitinib biochemical

Blood cancer; Angiogenesis; Cancer

Structure of Dovitinib biochemical

Dovitinib CHIR-258 Biochemical – Cat# MBS3604393

Product References and Citations for Dovitinib biochemical

1. Trudel S, et al. Blood. 2005 Apr 1; 105 (7):2941-8.
2. Lopes de Menezes DE, et al. Clin Cancer Res. 2005 Jul 15; 11 (14):5281-91.
3. Xin X, et al. Clin Cancer Res. 2006 Aug 15; 12 (16):4908-15.

Other Notes

Small volumes of Dovitinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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