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YM-1

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604405

YM-1 is a close derivative of MTK-077 that allosterically promotes Hsp70 binding to unfolded substrates, specificly binds to Hsp70 with Kd of 4.9 uM. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
YM-1, Biochemical
Full Product Name
YM-1
Product Synonym Names
YM1
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
417.97
Target
HSP
Receptor
HSP
Chemical Name
2-((Z)-((E)-3-Ethyl-5-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-oxothiazolidin-2-ylidene)methyl)-1-methylpyridin-1-ium chloride
SMILES
CCN1C(=CC2=CC=CC=[N+]2C)SC(=C3N(C4=CC=CC=C4S3)C)C1=O.[Cl-]
Molecular Formula
C20H20ClN3OS2
CAS Number
409086-68-6

Structure of YM-1 biochemical

Ym-1 Biochemical – Cat# MBS3604405

Product References and Citations for YM-1 biochemical

1. Wang AM, et al. Nat Chem Biol. 2013 Feb; 9 (2):112-8.
2. Morishima Y, et al. Biochemistry. 2011 Aug 23; 50 (33):7146-56.
3. Colvin TA, et al. Cancer Res. 2014 Sep 1; 74 (17):4731-40.

Other Notes

Small volumes of YM-1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for YM-1 purchase

MBS3604405 is a biochemical targeting YM-1.
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