Pazopanib (GW-786034B)

Name: Pazopanib (GW-786034B); MyBioSource
Brand: MyBioSource
SKU: MBS3604521
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604521

A potent, orally available, pan-VEGFR inhibitor with IC50 of 10, 30, and 47 nM for VEGFR-1, -2, and -3, respectively. More details

$220 / 10 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Pazopanib, Biochemical

Full Product Name

Pazopanib

Product Synonym Names

GW-786034B; GW-786034; GW786034

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

437.518

Suitability

DMSO: >=43mg/mL

Target

VEGFR

Receptor

c-Kit; PDGFR; VEGFR1; VEGFR2; VEGFR3

Chemical Name

Benzenesulfonamide, 5-[[4-[(2, 3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl

SMILES

O=S(C1=CC(NC2=NC=CC(N(C3=CC4=NN(C)C(C)=C4C=C3)C)=N2)=CC=C1C)(N)=O

Molecular Formula

C21H23N7O2S

CAS Number

444731-52-6

Product Categories/Family for Pazopanib biochemical

Kidney Cancer; Angiogenesis; Cancer

Product References and Citations for Pazopanib biochemical

1. Podar K, et al. Proc Natl Acad Sci U S A. 2006 Dec 19; 103 (51):19478-83.
2. Kumar R, et al. Mol Cancer Ther. 2007 Jul; 6 (7):2012-21.
3. Harris PA, et al. J Med Chem. 2008 Aug 14; 51 (15):4632-40.
4. Hurwitz HI, et al. Clin Cancer Res. 2009 Jun 15; 15 (12):4220-7.

Other Notes

Small volumes of Pazopanib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pazopanib purchase

MBS3604521 is a biochemical targeting Pazopanib.