Motesanib (AMG 706)

Name: Motesanib (AMG 706); MyBioSource
Brand: MyBioSource
SKU: MBS3604538
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604538

A potent, orally bioavailable, multikinase inhibitor inhibitor of VEGFR1/2/3, PDGFR and c-Kit with IC50 of 2-6 nM, 84 nM and 8 nM, respectively. More details

$215 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Motesanib, Biochemical

Full Product Name

Motesanib

Product Synonym Names

AMG 706; AMG-706

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

373.4509

Suitability

DMSO: >=30mg/mL

Target

VEGFR

Receptor

VEGFR1; VEGFR2; VEGFR3

Chemical Name

3-Pyridinecarboxamide, N-(2, 3-dihydro-3, 3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]

SMILES

CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C

Molecular Formula

C22H23N5O

CAS Number

453562-69-1

Product Categories/Family for Motesanib biochemical

Lung Cancer; Angiogenesis; Cancer

Product References and Citations for Motesanib biochemical

1. Polverino A, et al. Cancer Res. 2006 Sep 1; 66 (17):8715-21.
2. Sherman SI, et al. N Engl J Med. 2008 Jul 3; 359 (1):31-42.
3. Coxon A, et al. lin Cancer Res. 2009 Jan 1; 15 (1):110-8.
4. Caenepeel S, et al. J Exp Clin Cancer Res. 2010 Jul 15; 29:96.

Other Notes

Small volumes of Motesanib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Motesanib purchase

MBS3604538 is a biochemical targeting Motesanib.