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Tivozanib (AV-951)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604577

A highly potent inhibitor of pan-VEGFR with IC50s of 60/6.5/15 nM for VEGFR1/2/3. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tivozanib, Biochemical
Full Product Name
Tivozanib
Product Synonym Names
AV-951; AV951; AV 951
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
454.8631
Suitability
10mM in DMSO
Target
VEGFR
Receptor
EphB2; PDGFRalpha; VEGFR1; VEGFR2; VEGFR3
Chemical Name
Urea, N-[2-chloro-4-[(6, 7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)
SMILES
O=C(NC1=NOC(C)=C1)NC2=CC=C(OC3=CC=NC4=CC(OC)=C(OC)C=C34)C=C2Cl
Molecular Formula
C22H19ClN4O5
CAS Number
475108-18-0

Product References and Citations for Tivozanib biochemical

1. Nakamura K, et al. Cancer Res. 2006 Sep 15; 66 (18):9134-42.
2. Eskens FA, et al. Clin Cancer Res. 2011 Nov 15; 17 (22):7156-63.
3. Momeny M, et al. Sci Rep. 2017 Apr 6; 7:45954.

Other Notes

Small volumes of Tivozanib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tivozanib purchase

MBS3604577 is a biochemical targeting Tivozanib.
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