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NVP-AEW541 (AEW-541)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604584

NVP-AEW541 (AEW-541, AEW541) is a potent, and selective inhibitor of IGF-1R with IC50 of 86 nM. More details

$255 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NVP-AEW541, Biochemical
Full Product Name
NVP-AEW541
Product Synonym Names
AEW-541; AEW541; AEW 541; NVP AEW541
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
439.5521
Suitability
DMSO: >=51mg/mL
Target
IGF-1R
Receptor
FLT1; FLT3; IGF-1R; InsulinReceptor; Tek
Chemical Name
7H-Pyrrolo[2, 3-d]pyrimidin-4-amine, 7-[cis-3-(1-azetidinylmethyl)cyclobutyl]-5-[3-(phenylmethoxy)phenyl]
SMILES
NC1=C2C(N([C@H]3C[C@@H](CN4CCC4)C3)C=C2C5=CC=CC(OCC6=CC=CC=C6)=C5)=NC=N1
Molecular Formula
C27H29N5O
CAS Number
475489-16-8

Product References and Citations for NVP-AEW541 biochemical

1. Garci­a-Echeverri­a C, et al. Cancer Cell. 2004 Mar; 5 (3):231-9.
2. Scotlandi K, et al. Cancer Res. 2005 May 1; 65 (9):3868-76.
3. Tanno B, et al. Clin Cancer Res. 2006 Nov 15; 12 (22):6772-80.

Other Notes

Small volumes of NVP-AEW541 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NVP-AEW541 purchase

MBS3604584 is a biochemical targeting NVP-AEW541.
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