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AEE-788

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604665

A potent, orally bioavailable dual EGFR/VEGFR receptor tyrosine kinase inhibitor with IC50 of 2, 6, 77 and 59 nM for EGFR, ErbB2, KDR and Flt-1, respectively. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AEE-788, Biochemical
Full Product Name
AEE-788
Product Synonym Names
AEE 788; AEE788; NVP-AEE 788
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
440.5832
Suitability
DMSO: 10mM
Target
EGFR
Receptor
c-Abl; c-Fms; EGFR; FLT1; HER2/ErbB2
Chemical Name
7H-Pyrrolo[2, 3-d]pyrimidin-4-amine, 6-[4-[(4-ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]
SMILES
C[C@@H](NC1=C2C(NC(C3=CC=C(CN4CCN(CC)CC4)C=C3)=C2)=NC=N1)C5=CC=CC=C5
Molecular Formula
C27H32N6
CAS Number
497839-62-0

Product Categories/Family for AEE-788 biochemical

Brain Cancer; Angiogenesis; Cancer

Structure of AEE-788 biochemical

AEE-788 Biochemical – Cat# MBS3604665

Product References and Citations for AEE-788 biochemical

1. Traxler P, et al. Cancer Res. 2004 Jul 15; 64 (14):4931-41.
2. Goudar RK, et al. Mol Cancer Ther. 2005 Jan; 4 (1):101-12.
3. Park YW, et al. Clin Cancer Res. 2005 Mar 1; 11 (5):1963-73.

Other Notes

Small volumes of AEE-788 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AEE-788 purchase

MBS3604665 is a biochemical targeting AEE-788.
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