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Trimetrexate (CI-898)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604829

A quinazoline derivative and antifolate agent that fuctions as a dihydrofolate reductase (DHFR) inhibitor. More details

$345 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Trimetrexate, Biochemical
Full Product Name
Trimetrexate
Product Synonym Names
CI-898; NSC-249008; CI898; NSC249008
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
369.4176
Suitability
10mM in DMSO
Target
Antifolate
Receptor
Antifolate
Chemical Name
2, 4-Quinazolinediamine, 5-methyl-6-[[(3, 4, 5-trimethoxyphenyl)amino]methyl]
SMILES
NC1=NC(N)=C2C(C)=C(CNC3=CC(OC)=C(OC)C(OC)=C3)C=CC2=N1
Molecular Formula
C19H23N5O3
CAS Number
52128-35-5

Product References and Citations for Trimetrexate biochemical

1. Weir EC, et al. Cancer Res. 1982 May; 42 (5):1696-702.
2. Diddens H, et al. Cancer Res. 1983 Nov; 43 (11):5286-92.
3. Elslager EF, et al. J Med Chem. 1983 Dec; 26 (12):1753-60.
4. Wong BK, et al. Drug Metab Dispos. 1990 Nov-Dec; 18 (6):980-6.

Other Notes

Small volumes of Trimetrexate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Trimetrexate purchase

MBS3604829 is a biochemical targeting Trimetrexate.
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