APR-246 (PRIMA-1MET)

Name: APR-246 (PRIMA-1MET); MyBioSource
Brand: MyBioSource
SKU: MBS3604873
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604873

APR-246 (PRIMA-1MET) is a methylated derivative of PRIMA-1 that restores mutant p53 activity. More details

$250 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

APR-246, Biochemical

Full Product Name

APR-246

Product Synonym Names

PRIMA-1MET

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

199.25

Suitability

DMSO: 20mg/mL (<1mg/mL refers to the product slightly soluble or insoluble)

Target

MDM2-p53

Receptor

p53activator; TrxR1inhibitor

Chemical Name

2-(Hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one

SMILES

O=C1C(COC)(CO)N2CCC1CC2

Molecular Formula

C10H17NO3

CAS Number

5291-32-7

Product Categories/Family for APR-246 biochemical

Ovarian Cancer; Apoptosis; Cancer

Product References and Citations for APR-246 biochemical

1. Shen J, et al. Oncogene. 2008 Nov 20; 27 (51):6571-80.
2. Bykov VJ, et al. Oncogene. 2005 May 12; 24 (21):3484-91.
3. Rkaeus N, et al. Oncogene. 2010 Dec 9; 29 (49):6442-51.

Other Notes

Small volumes of APR-246 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APR-246 purchase

MBS3604873 is a biochemical targeting APR-246.