• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Tofacitinib citrate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604929

A potent, specific, orally active inhibitor of JAK3 with IC50 of 1 nM in cell-free assays; displays 20- to 100-fold less potency for JAK2 and JAK1 (IC50=20 nM and 112 nM, respectively). More details

$215 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tofacitinib citrate, Biochemical
Full Product Name
Tofacitinib citrate
Product Synonym Names
Tasocitinib citrate; CP-690550 citrate; CP 690550 citrate; CP690550 citrate
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
504.4931
Suitability
DMSO: >=122.5mg/mL
Target
JAK
Receptor
JAK1; JAK2; JAK3; Lck; ROCK2
Chemical Name
1-Piperidinepropanenitrile, 4-methyl-3-(methyl-7H-pyrrolo[2, 3-d]pyrimidin-4-ylamino)-beta-oxo-, (3R, 4R)-, 2-hydroxy-1, 2, 3-propanetricarboxylate(1:1)
SMILES
C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
Molecular Formula
C22H28N6O8
CAS Number
540737-29-9

Product Categories/Family for Tofacitinib citrate biochemical

Rheumatoid Arthritis; Angiogenesis; Inflammation/Immunology

Structure of Tofacitinib citrate biochemical

Tofacitinib Citrate Biochemical – Cat# MBS3604929

Product References and Citations for Tofacitinib citrate biochemical

1. Changelian PS, et al. Science. 2003 Oct 31; 302 (5646):875-8.
2. Jiang JK, et al. J Med Chem. 2008 Dec 25; 51 (24):8012-8.
3. Kudlacz E, et al. Am J Transplant. 2004 Jan; 4 (1):51-7.

Other Notes

Small volumes of Tofacitinib citrate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tofacitinib citrate purchase

MBS3604929 is a biochemical targeting Tofacitinib citrate.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000