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Vacquinol-1 (NSC 13316)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604943

Vacquinol-1 (NSC 13316) is a MKK4 (MAP2K4, MEK4) activator that induces vacuolization, induces ATP depletion in glioblastoma cells (IC50 = 3.14 uM) without affecting fibroblasts. More details

$505 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Vacquinol-1, Biochemical
Full Product Name
Vacquinol-1
Product Synonym Names
NSC 13316
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
352.862
Suitability
Ethanol: <1mg/mL
DMSO: 70mg/mL (164.4mM)
Water: <1mg/mL (<1mg/mL refers to the product slightly soluble or insoluble)
Target
MEK
Receptor
MKK4
Chemical Name
[2-(4-Chlorophenyl)quinolin-4-yl](piperidine-2-yl)methanol
SMILES
ClC1=CC=C(C2=NC(C=CC=C3)=C3C(C(O)C4NCCCC4)=C2)C=C1
Molecular Formula
C21H21ClN2O
CAS Number
5428-80-8

Product Categories/Family for Vacquinol-1 biochemical

Product References and Citations for Vacquinol-1 biochemical

1. Kitambi SS, et al. Cell. 2014 Apr 10; 157 (2):313-28.
2. Hammarstrm LG, et al. J Med Chem. 2016 Sep 22; 59 (18):8577-92.
3. Sander P, et al. Oncotarget. 2017 May 23; 8 (21):35124-35137.

Other Notes

Small volumes of Vacquinol-1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Vacquinol-1 purchase

MBS3604943 is a biochemical targeting Vacquinol-1.
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