Palbociclib (PD0332991)

Name: Palbociclib (PD0332991); MyBioSource
Brand: MyBioSource
SKU: MBS3605080
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605080

A potent and selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM; no inhibition for CDK2A (IC50>5 uM); inhibits MDA-MB453 cells with IC50 of 0.16 uM. More details

$235 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Palbociclib, Biochemical

Full Product Name

Palbociclib

Product Synonym Names

PD0332991; PD-0332991; PD 0332991

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

447.5327

Suitability

DMSO: 0.2mg/mL (Need ultrasonic or warming)

Target

CDK

Receptor

CDK4; CDK6

Chemical Name

Pyrido[2, 3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]

SMILES

CC(=O)C1=C(C)C2=CN=C(NC3=NC=C(C=C3)N3CCNCC3)N=C2N(C2CCCC2)C1=O

Molecular Formula

C24H29N7O2

CAS Number

571190-30-2

Product Categories/Family for Palbociclib biochemical

Breast Cancer; Angiogenesis; Cancer

Product References and Citations for Palbociclib biochemical

1. Toogood PL, et al. J Med Chem. 2005 Apr 7; 48 (7):2388-406.
2. Fry DW, et al. Mol Cancer Ther. 2004 Nov; 3 (11):1427-38.
3. Baughn LB, et al. Cancer Res. 2006 Aug 1; 66 (15):7661-7.

Other Notes

Small volumes of Palbociclib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Palbociclib purchase

MBS3605080 is a biochemical targeting Palbociclib.