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Deforolimus (AP-23573)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605088

MBS3605088 is a biochemical targeting Deforolimus. A potent, selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line. More details

$235 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Deforolimus, Biochemical
Full Product Name
Deforolimus
Product Synonym Names
AP-23573; MK-8669; Ridaforolimus
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
990.2061
Suitability
DMSO: >=44mg/mL
Target
mTOR
Receptor
mTOR
Chemical Name
Rapamycin, 42-(dimethylphosphinate)(9CI)
SMILES
[H][C@@]12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@H](CC(=O)[C@H](C)C=C(C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=CC=C(C)[C@H](C2)OC)[C@H](C)C[C@@H]1CC[C@@H](OP(C)(C)=O)[C@@H](C1)OC|r,c:31,50,t:46,48|
Molecular Formula
C53H84NO14P
CAS Number
572924-54-0

Product Categories/Family for Deforolimus biochemical

Breast Cancer; PI3K/Akt/mTOR signaling; Cancer

Structure of Deforolimus biochemical

Deforolimus AP-23573 Biochemical – Cat# MBS3605088

Product References and Citations for Deforolimus biochemical

1. Rivera VM, et al. Mol Cancer Ther. 2011 Jun; 10 (6):1059-71.
2. Legrier ME, et al. Cancer Res. 2007 Dec 1; 67 (23):11300-8.
3. Becker MA, et al. BMC Cancer. 2016 Oct 20; 16 (1):814.

Other Notes

Small volumes of Deforolimus biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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