Losmapimod (GSK-AHAB)

Name: Losmapimod (GSK-AHAB); MyBioSource
Brand: MyBioSource
SKU: MBS3605148
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605148

Losmapimod (GSK-AHAB, GW856553X, SB856553) is a selective, potent, orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38alpha and p38beta, respectively. More details

$215 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Losmapimod, Biochemical

Full Product Name

Losmapimod

Product Synonym Names

GSK-AHAB; GW856553X; SB856553; GW 856553X; SB 856553

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

383.4591

Suitability

DMSO: >=58mg/mL

Target

p38 MAPK

Receptor

p38alpha; p38beta

Chemical Name

3-Pyridinecarboxamide, 6-[5-[(cyclopropylamino)carbonyl]-3-fluoro-2-methylphenyl]-N-(2, 2-dimethylpropyl)

SMILES

O=C(C1=CC=C(C2=CC(C(NC3CC3)=O)=CC(F)=C2C)N=C1)NCC(C)(C)C

Molecular Formula

C22H26FN3O2

CAS Number

585543-15-3

Product Categories/Family for Losmapimod biochemical

Ischemia; MAPK/ERK Signaling; Cardiovascular Disease

Product References and Citations for Losmapimod biochemical

1. Willette RN, et al. J Pharmacol Exp Ther. 2009 Sep; 330 (3):964-70.
2. Cheriyan J, et al. Circulation. 2011 Feb 8; 123 (5):515-23.
3. Lomas DA, et al. J Clin Pharmacol. 2012 Mar; 52 (3):416-24.

Other Notes

Small volumes of Losmapimod biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Losmapimod purchase

MBS3605148 is a biochemical targeting Losmapimod.