Selumetinib (ARRY-142886)

Name: Selumetinib (ARRY-142886); MyBioSource
Brand: MyBioSource
SKU: MBS3605266
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605266

A highly potent and selective, ATP-uncompetitive inhibitor of MEK1/2 with IC50/Ki of 14.1 nM/22.6 nM for MEK1. More details

$235 / 25 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Selumetinib, Biochemical

Full Product Name

Selumetinib

Product Synonym Names

ARRY-142886; AZD-6244

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

457.6814

Suitability

DMSO: >=34mg/mL

Target

MEK

Receptor

MEK1

Chemical Name

1H-Benzimidazole-6-carboxamide, 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl

SMILES

O=C(C1=C(NC2=CC=C(Br)C=C2Cl)C(F)=C3C(N(C)C=N3)=C1)NOCCO

Molecular Formula

C17H15BrClFN4O3

CAS Number

606143-52-6

Product Categories/Family for Selumetinib biochemical

Skin Cancer; MAPK/ERK Signaling; Cancer

Product References and Citations for Selumetinib biochemical

1. Huynh H, et al. Mol Cancer Ther. 2007 Jan; 6 (1):138-46.
2. Yeh TC, et al. Clin Cancer Res. 2007 Mar 1; 13 (5):1576-83.
3. Davies BR, et al. Mol Cancer Ther. 2007 Aug; 6 (8):2209-19.

Other Notes

Small volumes of Selumetinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Selumetinib purchase

MBS3605266 is a biochemical targeting Selumetinib.