Apremilast (CC 10004)

Name: Apremilast (CC 10004); MyBioSource
Brand: MyBioSource
SKU: MBS3605282
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605282

Apremilast (CC-10004) is a potent, orally active PDE4 inhibitor with IC50 of 74 nM, inhibits TNF-alpha production in LPS-stimulated hPBMCs with IC50 of 77 nM. More details

$235 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Apremilast, Biochemical

Full Product Name

Apremilast

Product Synonym Names

CC 10004; CC10004; CC-10004

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

460.5002

Suitability

10mM in DMSO

Target

PDE

Receptor

PDE4

Chemical Name

Acetamide, N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2, 3-dihydro-1, 3-dioxo-1H-isoindol-4-yl]

SMILES

CC(NC1=CC=CC(C(N2[C@@H](C3=CC=C(OC)C(OCC)=C3)CS(=O)(C)=O)=O)=C1C2=O)=O

Molecular Formula

C22H24N2O7S

CAS Number

608141-41-9

Product Categories/Family for Apremilast biochemical

Psoriasis; Angiogenesis; Inflammation/Immunology

Product References and Citations for Apremilast biochemical

1. Man HW, et al. J Med Chem. 2009 Mar 26; 52 (6):1522-4.
2. McCann FE, et al. Arthritis Res Ther. 2010; 12 (3):R107.
3. Schafer PH, et al. Br J Pharmacol. 2010 Feb; 159 (4):842-55.
4. Gordon JN, et al. J Crohns Colitis. 2009 Sep; 3 (3):175-82.

Other Notes

Small volumes of Apremilast biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Apremilast purchase

MBS3605282 is a biochemical targeting Apremilast.