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AF-399 42016530

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605339

A potent CCR4 antagonist that blocked CCL22- and CCL17-mediated migration of human peripheral blood CD4+CD25+ Treg and Th2 cells ex-vivo and murine Tregs in-vivo. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AF-399 42016530, Biochemical
Full Product Name
AF-399 42016530
Product Synonym Names
AF-399/42016530
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
531.619
Target
Chemokine Receptor
Receptor
Chemokine Receptor
Chemical Name
4-(1-benzofuran-2-ylcarbonyl)-1-[5-(benzylsulfanyl)-1, 3, 4-thiadiazol-2-yl]-3-hydroxy-5-(2-thienyl)-1, 5-dihydro-2H-pyrrol-2-one.
Molecular Formula
C26H17N3O4S3
CAS Number
618864-56-5

Product Categories/Family for AF-399 42016530 biochemical

GPCR/G Protein

Product References and Citations for AF-399 42016530 biochemical

1. Klein A, et al. Oncotarget. 2017 May 9; 8 (19):31079-31091.
2. Bayry J, et al. Proc Natl Acad Sci U S A. 2008 Jul 22; 105 (29):10221-6.
3. Pere H, et al. Blood. 2011 Nov 3; 118 (18):4853-62.

Other Notes

Small volumes of AF-399 42016530 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AF-399 42016530 purchase

MBS3605339 is a biochemical targeting AF-399 42016530.
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