Nilotinib (AMN-107)

Name: Nilotinib (AMN-107); MyBioSource
Brand: MyBioSource
SKU: MBS3605436
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605436

A potent, selective, orally available inhibitor of both native and mutant Bcr-Abl with IC50 of 20-80 nM. More details

$220 / 50 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Nilotinib, Biochemical

Full Product Name

Nilotinib

Product Synonym Names

AMN-107; Tasigna; AMN107

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

529.5158

Suitability

DMSO: 28mg/mL

Target

Bcr-Abl

Receptor

Bcr-Abl

Chemical Name

Benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]

SMILES

CC1=CN(C=N1)C1=CC(NC(=O)C2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)=CC(=C1)C(F)(F)F

Molecular Formula

C28H22F3N7O

CAS Number

641571-10-0

Product Categories/Family for Nilotinib biochemical

Blood cancer; Angiogenesis; Cancer

Product References and Citations for Nilotinib biochemical

1. Weisberg E, et al. Cancer Cell. 2005 Feb; 7 (2):129-41.
2. O'Hare T, et al. Cancer Res. 2005 Jun 1; 65 (11):4500-5.
3. Golemovic M, et al. Clin Cancer Res. 2005 Jul 1; 11 (13):4941-7.
4. Stover EH, et al. Blood. 2005 Nov 1; 106 (9):3206-13.

Other Notes

Small volumes of Nilotinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nilotinib purchase

MBS3605436 is a biochemical targeting Nilotinib.