Nintedanib (BIBF-1120)

Name: Nintedanib (BIBF-1120); MyBioSource
Brand: MyBioSource
SKU: MBS3605492
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605492

A potent triple angiokinase (VEGFR/PDGFR/FGFR) inhibitor with IC50 of 5/38/18/104/5 nM for VEGFR-2/FGFR-1/PDGFRalpha/VEGFR-1/VEGFR-3, respectively. More details

$220 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Nintedanib, Biochemical

Full Product Name

Nintedanib

Product Synonym Names

BIBF-1120; BIBF1120

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: > 2 years
Shipping: Ice Pack

Molecular Weight

539.62

Suitability

10mM in DMSO

Target

VEGFR

Receptor

FLT3; Lck; VEGFR1; VEGFR2; VEGFR3; FGFR1; FGFR2; PDGFRalpha

Chemical Name

(Z)-methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

SMILES

CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N/C(=C3/C4=C(C=C(C=C4)C(=O)OC)NC3=O)/C5=CC=CC=C5

Molecular Formula

C31H33N5O4

CAS Number

656247-17-5

Product Categories/Family for Nintedanib biochemical

Lung Cancer; Angiogenesis; Cancer

Product References and Citations for Nintedanib biochemical

1. Roth GJ, et al. J Med Chem. 2009 Jul 23; 52 (14):4466-80.
2. Hilberg F, et al. Cancer Res. 2008 Jun 15; 68 (12):4774-82.
3. Kudo K, et al. Clin Cancer Res. 2011 Mar 15; 17 (6):1373-81.

Other Notes

Small volumes of Nintedanib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nintedanib purchase

MBS3605492 is a biochemical targeting Nintedanib.