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Nintedanib esylate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605493

Nintedanib esylate (BIBF1120 esylate) is a potent triple angiokinase (VEGFR/PDGFR/FGFR) inhibitor. More details

$215 / 10 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Nintedanib esylate, Biochemical
Full Product Name
Nintedanib esylate
Product Synonym Names
BIBF1120 esylate; BIBF-1120 esylate
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
649.7571
Suitability
10mM in DMSO
Target
VEGFR
Receptor
VEGFR1; VEGFR2; VEGFR3; FGFR1; FGFR2; FGFR3; PDGFRalpha; PDGFRbeta
Chemical Name
1H-Indole-6-carboxylic acid, 2, 3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-, ethanesulfonate(1:1)
SMILES
CCS(=O)(=O)O.CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O
Molecular Formula
C33H39N5O7S
CAS Number
656247-18-6

Product Categories/Family for Nintedanib esylate biochemical

Lung Cancer; Angiogenesis; Cancer

Structure of Nintedanib esylate biochemical

Nintedanib Esylate Biochemical – Cat# MBS3605493

Product References and Citations for Nintedanib esylate biochemical

1. Roth GJ, et al. J Med Chem. 2009 Jul 23; 52 (14):4466-80.
2. Hilberg F, et al. Cancer Res. 2008 Jun 15; 68 (12):4774-82.
3. Kudo K, et al. Clin Cancer Res. 2011 Mar 15; 17 (6):1373-81.

Other Notes

Small volumes of Nintedanib esylate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nintedanib esylate purchase

MBS3605493 is a biochemical targeting Nintedanib esylate.
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