Saframycin A (NSC 325663)

Name: Saframycin A (NSC 325663); MyBioSource
Brand: MyBioSource
SKU: MBS3605512
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605512

A heterocyclic quinone antibiotic that inhibits RNA synthesis in vivo and in vitro. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Saframycin A, Biochemical

Full Product Name

Saframycin A

Product Synonym Names

NSC 325663

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

562.579

Target

DNA/RNA Synthesis

Receptor

DNA/RNA Synthesis

Chemical Name

N-[[(6S, 7R, 9R, 14aS, 15R)-7-Cyano-1, 5, 6, 7, 9, 10, 13, 14, 14a, 15-decahydro-2, 11-dimethoxy-3, 12, 16-trimethyl-1, 4, 10, 13-tetraoxo-6, 15-imino-4H-isoquino[3, 2-b][3]benzazocin-9-yl]methyl]-2-oxopropanamide

SMILES

COC1=C(C(C2=C(C1=O)[C@@H](N3[C@H]([C@H]4N([C@@H]([C@@H]3C#N)CC5=C4C(C(OC)=C(C5=O)C)=O)C)C2)CNC(C(C)=O)=O)=O)C

Molecular Formula

C29H30N4O8

CAS Number

66082-27-7

Product Categories/Family for Saframycin A biochemical

Cell Cycle/DNA Damage

Product References and Citations for Saframycin A biochemical

1. Xing C, et al. Proc Natl Acad Sci U S A. 2004 Apr 20; 101 (16):5862-6.
2. Ishiguro K, et al. Biochemistry. 1978 Jun 27; 17 (13):2545-50.
3. Spencer JR, et al. Bioorg Med Chem Lett. 2006 Sep 15; 16 (18):4884-8.

Other Notes

Small volumes of Saframycin A biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Saframycin A purchase

MBS3605512 is a biochemical targeting Saframycin A.