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TGX-221

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605527

MBS3605527 is a biochemical targeting TGX-221. A potent, selective PI3K p110beta inhibitor with IC50 of 8.5 nM. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TGX-221, Biochemical
Full Product Name
TGX-221
Product Synonym Names
TGX221; TGX 221
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
364.4409
Suitability
10mM in DMSO
Target
PI3K
Receptor
p110alpha; p110beta; p110gamma; p110delta
Chemical Name
4H-Pyrido[1, 2-a]pyrimidin-4-one, 7-methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]
SMILES
O=C1C=C(N2CCOCC2)N=C3N1C=C(C)C=C3C(NC4=CC=CC=C4)C
Molecular Formula
C21H24N4O2
CAS Number
663619-89-4

Product Categories/Family for TGX-221 biochemical

PI3K/Akt/mTOR signaling; Cancer

Structure of TGX-221 biochemical

TGX-221 Biochemical – Cat# MBS3605527

Product References and Citations for TGX-221 biochemical

1. Frazzetto M, et al. Biochem J. 2008 Sep 15; 414 (3):383-90.
2. Sturgeon SA, et al. Eur J Pharmacol. 2008 Jun 10; 587 (1-3):209-15.
3. Chaussade C, et al. Biochem J. 2007 Jun 15; 404 (3):449-58.
4. Straub A, et al. Thromb Haemost. 2008 Mar; 99 (3):609-15.

Other Notes

Small volumes of TGX-221 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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