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GW 4869

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605605

A cell-permeable, symmetrical dihydroimidazolo-amide compound that acts as a potent, specific, non-competitive inhibitor of N-SMase (neutral sphingomyelinase) [IC50 = ~ 1 uM, rat brain; Km for sphingomyelin ~13 uM]. More details

$250 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GW 4869, Biochemical
Full Product Name
GW 4869
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
577.5
Suitability
Soluble in DMSO
Target
Phospholipase
Receptor
neutral sphingomyeliN/Ase
SMILES
C1NC(=NC1)C2=CC=C(C=C2)NC(=O)/C=C/C3=CC=C(C=C3)/C=C/C(=O)NC4=CC=C(C=C4)C5=NCCN5.Cl.Cl
Molecular Formula
C30H30Cl2N6O2
CAS Number
6823-69-4

Product Categories/Family for GW 4869 biochemical

Metabolic Enzyme/Protease; Cancer

Structure of GW 4869 biochemical

Gw 4869 Biochemical – Cat# MBS3605605

Product References and Citations for GW 4869 biochemical

1. Marchesini, N., et al. 2003. J. Biol. Chem. In press.

Other Notes

Small volumes of GW 4869 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GW 4869 purchase

MBS3605605 is a biochemical targeting GW 4869.
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