Neratinib (HKI-272)

Name: Neratinib (HKI-272); MyBioSource
Brand: MyBioSource
SKU: MBS3605677
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605677

A potent, highly selective, irreversible HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM in cell-free assays. More details

$215 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Neratinib, Biochemical

Full Product Name

Neratinib

Product Synonym Names

HKI-272; HKI272; HKI 272

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

557.0427

Suitability

DMSO: 6.4mg/mL (Need ultrasonic)

Target

EGFR

Receptor

EGFR; HER2; PDK1; Src; VEGFR2 (KDR)

Chemical Name

2-Butenamide, N-[4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-, (2E)

SMILES

CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C

Molecular Formula

C30H29ClN6O3

CAS Number

698387-09-6

Product Categories/Family for Neratinib biochemical

Breast Cancer; Angiogenesis; Cancer

Product References and Citations for Neratinib biochemical

1. Rabindran SK, et al. Cancer Res. 2004 Jun 1; 64 (11):3958-65.
2. Tsou HR, et al. J Med Chem. 2005 Feb 24; 48 (4):1107-31.
3. Ji H, et al. Proc Natl Acad Sci U S A. 2006 May 16; 103 (20):7817-22.

Other Notes

Small volumes of Neratinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Neratinib purchase

MBS3605677 is a biochemical targeting Neratinib.