LY2157299 (Galunisertib)

Name: Ly2157299 (Galunisertib); MyBioSource
Brand: MyBioSource
SKU: MBS3605687
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605687

LY2157299 (Galunisertib) is a potent, specific inhibitor of TGF-beta receptor I kinase ((TGF-betaRI) with IC50 of 56 nM. More details

$220 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LY2157299, Biochemical

Full Product Name

LY2157299

Product Synonym Names

Galunisertib; LY-2157299; LY 2157299

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

369.4192

Suitability

DMSO: >=47mg/mL

Target

TGFBR

Receptor

TbetaRI

Chemical Name

6-Quinolinecarboxamide, 4-[5, 6-dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1, 2-b]pyrazol-3-yl]

SMILES

O=C(C1=CC=C2N=CC=C(C3=C(CCC4)N4N=C3C5=NC(C)=CC=C5)C2=C1)N

Molecular Formula

C22H19N5O

CAS Number

700874-72-2

Product Categories/Family for LY2157299 biochemical

Blood cancer; TGF-beta/Smad; Cancer

Product References and Citations for LY2157299 biochemical

1. Zhou L, et al. Cancer Res. 2011 Feb 1; 71 (3):955-63.
2. Yoon JH, et al. EMBO Mol Med. 2013 Nov; 5 (11):1720-39.
3. Bhola NE, et al. J Clin Invest. 2013 Mar; 123 (3):1348-58.
4. Rodon J, et al. Clin Cancer Res. 2015 Feb 1; 21 (3):553-60.

Other Notes

Small volumes of LY2157299 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LY2157299 purchase

MBS3605687 is a biochemical targeting LY2157299.