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BX-912

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605693

BX-912 (BX912) is a potent, selective and ATP-competitive inhibitor of PDK1 with IC50 of 26 nM. More details

$250 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BX-912, Biochemical
Full Product Name
BX-912
Product Synonym Names
BX912; BX 912
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
471.3536
Suitability
10mM in DMSO
Target
PDK
Receptor
CDK2/CyclinE; Chk1; PDK1; PKA; VEGFR2 (KDR)
Chemical Name
1-Pyrrolidinecarboxamide, N-[3-[[5-bromo-4-[[2-(1H-imidazol-5-yl)ethyl]amino]-2-pyrimidinyl]amino]phenyl]
SMILES
O=C(N1CCCC1)NC2=CC=CC(NC3=NC=C(Br)C(NCCC4=CNC=N4)=N3)=C2
Molecular Formula
C20H23BrN8O
CAS Number
702674-56-4

Product Categories/Family for BX-912 biochemical

PI3K/Akt/mTOR signaling; Cancer

Structure of BX-912 biochemical

Bx-912 Biochemical – Cat# MBS3605693

Product References and Citations for BX-912 biochemical

1. Feldman RI, et al. J Biol Chem. 2005 May 20; 280 (20):19867-74.
2. Mashukova A, et al. Mol Biol Cell. 2012 May; 23 (9):1664-74.
3. Sturm EM, et al. Eur J Immunol. 2015 May; 45 (5):1548-59.

Other Notes

Small volumes of BX-912 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BX-912 purchase

MBS3605693 is a biochemical targeting BX-912.
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