GSK 356278

Name: GSK 356278; MyBioSource
Brand: MyBioSource
SKU: MBS3605755
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605755

A potent, selective, brain-penetrant and orally bioavailable phosphodiesterase 4 (PDE4) inhibitor with pIC50 of 8.8 (PDE4B); equally inhibits PDE4A and PDE4Dwith pIC50 of 8.6 and 8.7. More details

$215 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GSK 356278, Biochemical

Full Product Name

GSK 356278

Product Synonym Names

GSK356278; GSK-356278

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

439.538

Target

PDE

Receptor

PDE

Chemical Name

5-(5-((2, 4-dimethylthiazol-5-yl)methyl)-1, 3, 4-oxadiazol-2-yl)-1-ethyl-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3, 4-b]pyridin-4-amine

SMILES

CCN1N=CC2=C(NC3CCOCC3)C(C4=NN=C(CC5=C(C)N=C(C)S5)O4)=CN=C21

Molecular Formula

C21H25N7O2S

CAS Number

720704-34-7

Product Categories/Family for GSK 356278 biochemical

Anxiety; Angiogenesis; Neurological Disease

Product References and Citations for GSK 356278 biochemical

1. Rutter AR, et al. J Pharmacol Exp Ther. 2014 Jul; 350 (1):153-63.
2. van der Aart J, et al. J Cereb Blood Flow Metab. 2017 Jan 1:271678X17720868.

Other Notes

Small volumes of GSK 356278 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK 356278 purchase

MBS3605755 is a biochemical targeting GSK 356278.

GSK 356278

Product Overview

Product Categories/Family for GSK 356278 biochemical

Structure of GSK 356278 biochemical

Related Product Information for GSK 356278 biochemical

Product References and Citations for GSK 356278 biochemical

Other Notes

Searchable Terms for GSK 356278 purchase