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Barasertib (AZD-1152)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605762

A potent, highly selective Aurora B inhibitor with IC50 of 0.37 nM; displays >1,000-fold selectivity over Aurora B kinase. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Barasertib, Biochemical
Full Product Name
Barasertib
Product Synonym Names
AZD-1152; AZD1152
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
587.5398
Suitability
DMSO: >=33mg/mL
Target
Aurora Kinase
Receptor
Aurora Kinase
Chemical Name
1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)
SMILES
O=P(O)(OCCN(CC)CCCOC1=CC2=NC=NC(NC3=NNC(CC(NC4=CC=CC(F)=C4)=O)=C3)=C2C=C1)O
Molecular Formula
C26H31FN7O6P
CAS Number
722543-31-9

Product References and Citations for Barasertib biochemical

1. Mortlock AA, et al. J Med Chem. 2007 May 3; 50 (9):2213-24.
2. Yang J, et al. Blood. 2007 Sep 15; 110 (6):2034-40.
3. Wilkinson RW, Clin Cancer Res. 2007 Jun 15; 13 (12):3682-8.et al.
4. Evans RP, et al. Br J Haematol. 2008 Feb; 140 (3):295-302.

Other Notes

Small volumes of Barasertib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Barasertib purchase

MBS3605762 is a biochemical targeting Barasertib.
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