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NVP-AUY922 (Luminespib)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605848

A potent and selective HSP90 inhibitor with IC50 of 21 and 7.8 nM for HSP90beta and HSP90alpha, respectively. More details

$235 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NVP-AUY922, Biochemical
Full Product Name
NVP-AUY922
Product Synonym Names
Luminespib; AUY922; VER-52296; VER-52296; VER52296
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
465.5414
Suitability
DMSO: >=62mg/mL
Target
HSP
Receptor
HSP90alpha; HSP90beta
Chemical Name
3-Isoxazolecarboxamide, 5-[2, 4-dihydroxy-5-(1-methylethyl)phenyl]-N-ethyl-4-[4-(4-morpholinylmethyl)phenyl]
SMILES
O=C(C1=NOC(C2=CC(C(C)C)=C(O)C=C2O)=C1C3=CC=C(CN4CCOCC4)C=C3)NCC
Molecular Formula
C26H31N3O5
CAS Number
747412-49-3

Product References and Citations for NVP-AUY922 biochemical

1. Brough PA, et al. J Med Chem. 2008 Jan 24; 51 (2):196-218.
2. Eccles SA, et al. Cancer Res. 2008 Apr 15; 68 (8):2850-60.
3. Jensen MR, et al. Breast Cancer Res. 2008; 10 (2):R33.
4. Stuhmer T, et al. Leukemia. 2008 Aug; 22 (8):1604-12.

Other Notes

Small volumes of NVP-AUY922 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NVP-AUY922 purchase

MBS3605848 is a biochemical targeting NVP-AUY922.
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