Atopaxar (E-5555)

Name: Atopaxar (E-5555); MyBioSource
Brand: MyBioSource
SKU: MBS3605857
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605857

A potent, reversible PAR-1 antagonist with IC50 of 19 nM; shows potent inhibitory effects on human platelet aggregation induced by thrombin and TRAP with IC50 of 64 nM and 31 nM, respectively. More details

$295 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Atopaxar, Biochemical

Full Product Name

Atopaxar

Product Synonym Names

E-5555; E5555

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

527.6374

Target

PAR

Receptor

PAR-1

Chemical Name

2-(5, 6-Diethoxy-7-fluoro-1, 3-dihydro-1-imino-2H-isoindol-2-yl)-1-[3-(1, 1-dimethylethyl)-4-methoxy-5-(4-morpholinyl)phenyl]ethanone

SMILES

COC1=C(N2CCOCC2)C=C(C(CN(CC3=C4C(F)=C(OCC)C(OCC)=C3)C4=N)=O)C=C1C(C)(C)C

Molecular Formula

C29H38FN3O5

CAS Number

751475-53-3

Product Categories/Family for Atopaxar biochemical

Thrombosis; GPCR/G Protein; Cardiovascular Disease

Product References and Citations for Atopaxar biochemical

1. Serebruany VL, et al. Thromb Haemost. 2009 Jul; 102 (1):111-9.
2. Angiolillo DJ, et al. Eur Heart J. 2010 Jan; 31 (1):17-28.
3. Kogushi M, et al. Eur J Pharmacol. 2011 Apr 25; 657 (1-3):131-7.

Other Notes

Small volumes of Atopaxar biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Atopaxar purchase

MBS3605857 is a biochemical targeting Atopaxar.