Volasertib (BI 6727)

Name: Volasertib (BI 6727); MyBioSource
Brand: MyBioSource
SKU: MBS3605869
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605869

Volasertib (BI 6727) is a potent, selective Polo-like kinase (PLK) inhibitor with IC50 of 0.87, 5 and 56 nM for PLK1, 2 and 3, respectively. More details

$235 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Volasertib, Biochemical

Full Product Name

Volasertib

Product Synonym Names

BI 6727; BI-6727; BI6727

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

618.8126

Suitability

10mM in DMSO

Target

PLK

Receptor

PLK1

Chemical Name

Benzamide, N-[trans-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5, 6, 7, 8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino]-3-methoxy

SMILES

O=C(N[C@H]1CC[C@@H](N2CCN(CC3CC3)CC2)CC1)C4=CC=C(NC(N=C5N(C(C)C)[C@@H]6CC)=NC=C5N(C)C6=O)C(OC)=C4

Molecular Formula

C34H50N8O3

CAS Number

755038-65-4

Product Categories/Family for Volasertib biochemical

Blood cancer; Cell Cycle/DNA Damage; Cancer

Product References and Citations for Volasertib biochemical

1. Rudolph D, et al. Clin Cancer Res. 2009 May 1; 15 (9):3094-102.
2. Grinshtein N, et al. Cancer Res. 2011 Feb 15; 71 (4):1385-95.
3. Schffski P, et al. Eur J Cancer. 2012 Jan; 48 (2):179-86.
4. Sanhaji M, et al. Cell Cycle. 2012 Feb 1; 11 (3):543-53.

Other Notes

Small volumes of Volasertib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Volasertib purchase

MBS3605869 is a biochemical targeting Volasertib.