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Debromohymenialdisine (SKF-108753)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605873

A marine sponge alkaloid that inhibits Chk1 and Chk2 with IC50 of 3 and 3.5 uM, respectively; also inhibits MAP kinase kinase 1 (IC50=881 nM), GSK3beta (IC50=1.39 uM), and CDK5/p25 (IC50=9.12 uM). More details

$985 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Debromohymenialdisine, Biochemical
Full Product Name
Debromohymenialdisine
Product Synonym Names
SKF-108753; SKF108753
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
245.2
Target
Chk
Receptor
Chk
Chemical Name
(4Z)-4-(2-amino-1, 5-dihydro-5-oxo-4H-imidazol-4-ylidene)-4, 5, 6, 7-tetrahydro-pyrrolo[2, 3-c]azepin-8(1H)-one
SMILES
O=C(C1=C/2C=CN1)NCCC2=C3N=C(N)NC/3=O
Molecular Formula
C11H11N5O2
CAS Number
75593-17-8

Product Categories/Family for Debromohymenialdisine biochemical

Product References and Citations for Debromohymenialdisine biochemical

1. Curman D, et al. J Biol Chem. 2001 May 25; 276 (21):17914-9.
2. Saleem RS, et al. Bioorg Med Chem. 2012 Feb 15; 20 (4):1475-81.
3. Jobson AG, et al. Mol Pharmacol. 2007 Oct; 72 (4):876-84.

Other Notes

Small volumes of Debromohymenialdisine biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Debromohymenialdisine purchase

MBS3605873 is a biochemical targeting Debromohymenialdisine.
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