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GNF-2

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605932

A potent, allosteric, non-ATP competitive Bcr-Abl inhibitor that shows exclusive antiproliferative activity toward Bcr-abl-transformed cells. More details

$215 / 1mL*10mM (in DMSO) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GNF-2, Biochemical
Full Product Name
GNF-2
Product Synonym Names
GNF 2; GNF2
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
374.3166
Suitability
DMSO: >=45mg/mL
Target
Bcr-Abl
Receptor
Bcr-Abl (K562cellline); Bcr-Abl (SUP-B15cellline)
Chemical Name
Benzamide, 3-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]
SMILES
O=C(N)C1=CC=CC(C2=NC=NC(NC3=CC=C(OC(F)(F)F)C=C3)=C2)=C1
Molecular Formula
C18H13F3N4O2
CAS Number
778270-11-4

Product Categories/Family for GNF-2 biochemical

Angiogenesis; Cancer

Structure of GNF-2 biochemical

GNF-2 Biochemical – Cat# MBS3605932

Product References and Citations for GNF-2 biochemical

1. Adrian FJ, et al. Nat Chem Biol. 2006 Feb; 2 (2):95-102.
2. Choi Y, et al. J Biol Chem. 2009 Oct 16; 284 (42):29005-14.
3. Clark MJ, et al. Cell Chem Biol. 2016 Apr 21; 23 (4):443-52.

Other Notes

Small volumes of GNF-2 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNF-2 purchase

MBS3605932 is a biochemical targeting GNF-2.
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