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Roxadustat (FG4592)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606019

Roxadustat (FG4592, FG-4592) is a potent, orally available HIF prolyl hydroxylase (HIF-PHD) with IC50 of 591.4 nM. More details

$215 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Roxadustat, Biochemical
Full Product Name
Roxadustat
Product Synonym Names
FG4592; FG-4592
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
352.3407
Suitability
DMSO: >=46mg/mL
Target
HIF/HIF Prolyl-hydroxylase
Receptor
HIF-PH
Chemical Name
Glycine, N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]
SMILES
O=C(O)CNC(C1=C(O)C2=C(C(C)=N1)C=C(OC3=CC=CC=C3)C=C2)=O
Molecular Formula
C19H16N2O5
CAS Number
808118-40-3

Product References and Citations for Roxadustat biochemical

1. Besarab A, et al. J Am Soc Nephrol. 2016 Apr; 27 (4):1225-33.
2. Wu Y, et al. J Med Chem. 2018 Jun 28; 61 (12):5332-5349.
3. Provenzano R, et al. Clin J Am Soc Nephrol. 2016 Jun 6; 11 (6):982-91.
4. Jain IH, et al. Science. 2016 Apr 1; 352 (6281):54-61.

Other Notes

Small volumes of Roxadustat biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Roxadustat purchase

MBS3606019 is a biochemical targeting Roxadustat.
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