AT-7519

Name: At-7519; MyBioSource
Brand: MyBioSource
SKU: MBS3606133
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606133

A potent CDK2 inhibitor with IC50 of 47 nM; also inhibits CDK1/4/5 with IC50 of 190/67/18 nM and shows selectivity over some kinases (Aurora A, IR kinase, MEK, PDK1, c-Abl, IC50>10 uM). More details

$235 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AT-7519, Biochemical

Full Product Name

AT-7519

Product Synonym Names

AT 7519; AT7519

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

382.2445

Suitability

10mM in DMSO

Target

CDK

Receptor

CDK2/CyclinA; CDK4/CyclinD1; CDK5/p35; CDK9/CyclinT; GSK-3beta

Chemical Name

1H-Pyrazole-3-carboxamide, 4-[(2, 6-dichlorobenzoyl)amino]-N-4-piperidinyl

SMILES

c1cc(c(c(c1)Cl)C(=O)Nc2c[nH]nc2C(=O)NC3CCNCC3)Cl

Molecular Formula

C16H17Cl2N5O2

CAS Number

844442-38-2

Product Categories/Family for AT-7519 biochemical

Blood cancer; Angiogenesis; Cancer

Product References and Citations for AT-7519 biochemical

1. Wyatt PG, et al. J Med Chem. 2008 Aug 28; 51 (16):4986-99.
2. Squires MS, et al. Mol Cancer Ther. 2009 Feb; 8 (2):324-32.
3. Dolman ME, et al. Clin Cancer Res. 2015 Nov 15; 21 (22):5100-9.

Other Notes

Small volumes of AT-7519 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AT-7519 purchase

MBS3606133 is a biochemical targeting AT-7519.

AT-7519

Product Overview

Product Categories/Family for AT-7519 biochemical

Structure of AT-7519 biochemical

Related Product Information for AT-7519 biochemical

Product References and Citations for AT-7519 biochemical

Other Notes

Searchable Terms for AT-7519 purchase