Bitopertin (RG1678)

Name: Bitopertin (RG1678); MyBioSource
Brand: MyBioSource
SKU: MBS3606139
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606139

A potent and selective GlyT1 inhibitor with EC50 of 30 nM; no activity for GlyT2, hERG, CYP450 enzymes above 10 uM. More details

$220 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Bitopertin, Biochemical

Full Product Name

Bitopertin

Product Synonym Names

RG1678; RO4917838; RG-1678; RG 1678; RO-4917838; RO 4917838

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

543.455

Suitability

10mM in DMSO

Target

GlyT

Receptor

GlyT1

Chemical Name

Methanone, [4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl][5-(methylsulfonyl)-2-[(1S)-2, 2, 2-trifluoro-1-methylethoxy]phenyl]

SMILES

FC1=C(N2CCN(C(C3=C(O[C@H](C(F)(F)F)C)C=CC(S(C)(=O)=O)=C3)=O)CC2)N=CC(C(F)(F)F)=C1

Molecular Formula

C21H20F7N3O4S

CAS Number

845614-11-1

Product Categories/Family for Bitopertin biochemical

Schizophrenia; Membrane Transporter/Ion Channel; Neurological Disease

Product References and Citations for Bitopertin biochemical

1. Pinard E, et al. J Med Chem. 2010 Jun 24; 53 (12):4603-14.
2. Alberati D, et al. Neuropharmacology. 2012 Feb; 62 (2):1152-613. Martin-Facklam M, et al. Neuropsychopharmacology. 2013 Feb; 38 (3):504-12.

Other Notes

Small volumes of Bitopertin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Bitopertin purchase

MBS3606139 is a biochemical targeting Bitopertin.