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Bitopertin R enantiomer

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606140

MBS3606140 is a biochemical targeting Bitopertin R enantiomer. A potent and selective GlyT1 inhibitor with EC50 of 54 nM. More details

$1265 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Bitopertin R enantiomer, Biochemical
Full Product Name
Bitopertin R enantiomer
Product Synonym Names
RG-1678 R enantiomer; RO-4917838 R enantiomer
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
543.455
Suitability
10mM in DMSO
Target
GlyT
Receptor
GlyT
Chemical Name
Methanone, [4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl][5-(methylsulfonyl)-2-[(1R)-2, 2, 2-trifluoro-1-methylethoxy]phenyl]
SMILES
FC1=CC(C(F)(F)F)=CN=C1N2CCN(C(C3=CC(S(=O)(C)=O)=CC=C3O[C@@H](C(F)(F)F)C)=O)CC2
Molecular Formula
C21H20F7N3O4S
CAS Number
845614-12-2

Product Categories/Family for Bitopertin R enantiomer biochemical

Schizophrenia; Membrane Transporter/Ion Channel; Neurological Disease

Structure of Bitopertin R enantiomer biochemical

Bitopertin R Enantiomer Biochemical – Cat# MBS3606140

Product References and Citations for Bitopertin R enantiomer biochemical

1. Pinard E, et al. J Med Chem. 2010 Jun 24; 53 (12):4603-14.
2. Alberati D, et al. Neuropharmacology. 2012 Feb; 62 (2):1152-613. Martin-Facklam M, et al. Neuropsychopharmacology. 2013 Feb; 38 (3):504-12.

Other Notes

Small volumes of Bitopertin R enantiomer biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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