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ML-385

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606143

A first-in-class small molecule inhibitor of NRF2 that binds to Neh1 DNA binding domain of NRF2 (IC50=1.9 uM) and inhibits the downstream target gene expression. More details

$235 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ML-385, Biochemical
Full Product Name
ML-385
Product Synonym Names
ML 385; ML385
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
507.6459
Suitability
DMSO: >=30mg/mL
Target
Keap1-Nrf2
Receptor
Nrf2
Chemical Name
1, 3-Benzodioxole-5-acetamide, N-[4-[2, 3-dihydro-1-(2-methylbenzoyl)-1H-indol-5-yl]-5-methyl-2-thiazolyl]
SMILES
O=C(NC1=NC(C2=CC3=C(N(C(C4=CC=CC=C4C)=O)CC3)C=C2)=C(C)S1)CC5=CC=C(OCO6)C6=C5
Molecular Formula
C31H29N3O2S
CAS Number
846557-71-9

Product Categories/Family for ML-385 biochemical

Lung Cancer; Nuclear Receptor/Transcription Factor; Cancer

Structure of ML-385 biochemical

Ml-385 Biochemical – Cat# MBS3606143

Product References and Citations for ML-385 biochemical

1. Singh A, et al. ACS Chem Biol. 2016 Nov 18; 11 (11):3214-3225.

Other Notes

Small volumes of ML-385 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ML-385 purchase

MBS3606143 is a biochemical targeting ML-385.
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