Sapitinib (AZD-8931)

Name: Sapitinib (AZD-8931); MyBioSource
Brand: MyBioSource
SKU: MBS3606161
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606161

Sapitinib (AZD-8931, AZD8931) is a equipotent, reversible inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4. 3 and 4 nM (phosphorylation inhibition), respectively. More details

$215 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Sapitinib, Biochemical

Full Product Name

Sapitinib

Product Synonym Names

AZD-8931; AZD8931

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

473.9277

Suitability

DMSO: >=33mg/mL

Target

EGFR

Receptor

EGFR; HER2/ErbB2

Chemical Name

1-Piperidineacetamide, 4-[[4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-N-methyl

SMILES

O=C(NC)CN1CCC(OC2=CC3=C(NC4=CC=CC(Cl)=C4F)N=CN=C3C=C2OC)CC1

Molecular Formula

C23H25ClFN5O3

CAS Number

848942-61-0

Product Categories/Family for Sapitinib biochemical

Colon Cancer; Angiogenesis; Cancer

Product References and Citations for Sapitinib biochemical

1. Hickinson DM, et al. Clin Cancer Res. 2010 Feb 15; 16 (4):1159-69.
2. Singleton KR, et al. Mol Pharmacol. 2013 Apr; 83 (4):882-93.
3. Barlaam B, et al. ACS Med Chem Lett. 2013 May 31; 4 (8):742-6.
4. Mu Z, et al. J Exp Clin Cancer Res. 2014 May 30; 33:47.

Other Notes

Small volumes of Sapitinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Sapitinib purchase

MBS3606161 is a biochemical targeting Sapitinib.