Foretinib (XL880)

Name: Foretinib (XL880); MyBioSource
Brand: MyBioSource
SKU: MBS3606162
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606162

Foretinib (XL880, GSK1363089, GSK089, EXEL-2880) is a potent, multikinase inhibitor that inhibits c-Met and VEGFR, also KIT, Flt-3, PDGFRbeta, and Tie-2. More details

$215 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Foretinib, Biochemical

Full Product Name

Foretinib

Product Synonym Names

XL880; GSK1363089; GSK089; EXEL-2880

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

632.6537

Suitability

DMSO: >=38mg/mL

Target

c-Met/HGFR

Receptor

Met; RON; Tie-2; VEGFR2 (KDR); VEGFR3/FLT4; KDR; Flt-4; Flt-3

Chemical Name

1, 1-Cyclopropanedicarboxamide, N-[3-fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N'-(4-fluorophenyl)

SMILES

O=C(C1(C(NC2=CC=C(F)C=C2)=O)CC1)NC3=CC=C(OC4=CC=NC5=CC(OCCCN6CCOCC6)=C(OC)C=C45)C(F)=C3

Molecular Formula

C34H34F2N4O6

CAS Number

849217-64-7

Product Categories/Family for Foretinib biochemical

Lung Cancer; Angiogenesis; Cancer

Product References and Citations for Foretinib biochemical

1. Qian F, et al. Cancer Res. 2009 Oct 15; 69 (20):8009-16.
2. Liu L, et al. Cancer Res. 2009 Sep 1; 69 (17):6871-8.
3. Eder JP, et al. Clin Cancer Res. 2010 Jul 1; 16 (13):3507-16.

Other Notes

Small volumes of Foretinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Foretinib purchase

MBS3606162 is a biochemical targeting Foretinib.