Cabozantinib (XL184)

Name: Cabozantinib (XL184); MyBioSource
Brand: MyBioSource
SKU: MBS3606163
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606163

Cabozantinib (XL184, BMS-907351) is a potent multi-kinase inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50 of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively. More details

$220 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Cabozantinib, Biochemical

Full Product Name

Cabozantinib

Product Synonym Names

XL184; BMS-907351; XL-184; XL184

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

501.5057

Suitability

DMSO: >=30mg/mL

Target

VEGFR

Receptor

AXL; c-Met; Kit; VEGFR2/KDR; VEGFR3/FLT4; VEGFR2; MET; MET (Y1248H); RET; FLT3

Chemical Name

1, 1-Cyclopropanedicarboxamide, N'-[4-[(6, 7-dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)

SMILES

COC1=CC2=NC=CC(OC3=CC=C(C=C3)N(C(=O)C3(CC3)C(N)=O)C3=CC=C(F)C=C3)=C2C=C1OC

Molecular Formula

C28H24FN3O5

CAS Number

849217-68-1

Product Categories/Family for Cabozantinib biochemical

Kidney Cancer; Angiogenesis; Cancer

Product References and Citations for Cabozantinib biochemical

1. You WK, et al. Cancer Res. 2011 Jul 15; 71 (14):4758-68.
2. Durante C, et al. Expert Opin Investig Drugs. 2011 Mar; 20 (3):407-413.
3. Torres KE, et al. Clin Cancer Res. 2011 Jun 15; 17 (12):3943-55.
4. Kurzrock R, et al. J Clin Oncol. 2011 Jul 1; 29 (19):2660-6.

Other Notes

Small volumes of Cabozantinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cabozantinib purchase

MBS3606163 is a biochemical targeting Cabozantinib.