Danoprevir (ITMN-191)

Name: Danoprevir (ITMN-191); MyBioSource
Brand: MyBioSource
SKU: MBS3606178
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606178

A potent, highly selective, orally available, peptidomimetic HCV NS3/4A protease inhibitor with IC50 of 0.2-0.4 nM (GT1a, 1b, 4, 5 and 6), 1.6 nM (GT2b). More details

$295 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Danoprevir, Biochemical

Full Product Name

Danoprevir

Product Synonym Names

ITMN-191; R-7227; RO-5190591; RG-7227

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

731.8312

Suitability

10mM in DMSO

Target

HCV

Receptor

HCVNS3/4Aprotease

Chemical Name

2H-Isoindole-2-carboxylic acid, 4-fluoro-1, 3-dihydro-, (2R, 6S, 13aS, 14aR, 16aS)-14a-[[(cyclopropylsulfonyl)amino]carbonyl]-6-[[(1, 1-dimethylethoxy)carbonyl]amino]-1, 2, 3, 5, 6, 7, 8, 9, 10, 11, 13a, 14, 14a, 15, 16, 16a-hexadecahydro-5, 16-dioxocyclopropa[e]pyrrolo[1, 2-a]

SMILES

O=C(N1CC2=C(C(F)=CC=C2)C1)O[C@@H](C3)C[C@](C(N[C@@](C4)(C(NS(=O)(C5CC5)=O)=O)[C@]4([H])/C=CCCCCCC6NC(OC(C)(C)C)=O)=O)([H])N3C6=O

Molecular Formula

C35H46FN5O9S

CAS Number

850876-88-9

Product Categories/Family for Danoprevir biochemical

HCV Infection; Microbiology/Virology; Infection

Product References and Citations for Danoprevir biochemical

1. Bae A, et al. Antimicrob Agents Chemother. 2010 Dec; 54 (12):5288-97.
2. Moucari R, et al. Gut. 2010 Dec; 59 (12):1694-8.
3. Jiang Y, et al. J Med Chem. 2014 Mar 13; 57 (5):1753-69.
4. Schaefer CJ, et al. Antimicrob Agents Chemother. 2011 Jul; 55 (7):3125-32.

Other Notes

Small volumes of Danoprevir biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Danoprevir purchase

MBS3606178 is a biochemical targeting Danoprevir.